• Weight loss

Which weight loss medication works for you?

Written by: Editors

Modified on: 

A weight loss medication can assist in tackling overweight. The emphasis is on can, as it is not a miracle solution. However, it does support the process of losing weight. Lifestyle and a balanced diet form the foundation of good health and the path towards a healthy weight. Sometimes, though, this is not enough to reach your goal. In such cases, combining these efforts with weight loss medication may provide an answer. You will need to meet certain criteria to qualify for these medicines. Which one is most suitable for you depends on your individual circumstances. Here, we take a closer look at overweight and provide an overview of the various weight loss medications available.

What is overweight?

Usually,  overweight  or obesity is determined using BMI. A BMI between 18 and 25 indicates a healthy weight. From 25 onwards, it is considered overweight, and from 30, obesity. However, this is not the only factor considered. Doctors also often assess waist circumference. For men, the maximum waist circumference is 102 cm; for women, it is 88 cm. A larger waist circumference indicates excess body fat and, like a high BMI, can increase health risks. 

What are the health risks?

With overweight or obesity, there is an increased risk of health problems. These include: 

This does not mean that everyone with overweight or obesity will develop these health issues or conditions. It simply means the risk is higher. With the right diet or a  meal plan  and regular physical activity, the likelihood of these conditions and complaints is reduced, and the chance of losing weight is improved. If this is not effective, weight loss medication could be an option. 

Treatment with weight loss medications

Several weight loss medications have been approved for use in Europe. These are often only available on prescription and are intended for people with a BMI of 30 or higher, or a BMI of 27 or higher in combination with an obesity-related condition. Below is an overview of the available weight loss medications. Which is most suitable depends on lifestyle, medical history, and personal preferences. 

Comparison of available weight loss medications 

Characteristic

Wegovy

Saxenda

Mounjaro

Mysimba

Xenical / Orlistat

Active ingredient

Semaglutide

Liraglutide

Tirzepatide

Naltrexone/ Bupropion

Orlistat

Form of administration

Injection in the abdomen, upper arm, or thigh

Injection in the abdomen, upper arm, or thigh

Injection in the abdomen, upper arm, or thigh

Tablet

Capsule

Possible weight loss (varies per person)

15%

10%

Up to 20%

5-10%

5-10%

How does it work?

Reduces appetite and slows gastric emptying

Reduces appetite

Reduces appetite and slows gastric emptying

Suppresses hunger

Reduces fat absorption

Frequency

Once a week

Once a day

Once a week

Daily as prescribed

Three times a day

Maximum dosage

2.4mg

3mg

15mg

4 tablets

3 capsules

Side effects

Dizziness, gastrointestinal complaints, headache

Nausea, dizziness, gastrointestinal complaints

Gastrointestinal complaints, diarrhoea, slight increase in heart rate

Nausea, headache, stomach ache

Loose stools, headache, abdominal pain

Prescription required?

Yes

Yes

Yes

Yes

Yes

This comparison table lists some of the side effects. For a full overview, please refer to the patient information leaflet for the relevant medication.

What can you do yourself?

A balanced diet and lifestyle can help you maintain a healthy weight or lose weight. Some tips that may help include: 

  • Fresh vegetables and fruit: low in calories but rich in fibre, vitamins, and minerals. 
  • Proteins: essential for building and maintaining muscle, and help you feel full. 
  • Healthy fats: beneficial for your eyes, skin, heart, and brain. They can help you feel satisfied and reduce cravings. 
  • Fibre: supports healthy digestion and slows the rise in blood sugar, helping to reduce tiredness and cravings for sweet snacks. 
  • Drink plenty of water: helps your body to eliminate waste more quickly and gives a feeling of fullness. 

Combine this with regular physical activity for the best results. Cardio exercises together with strength training help to maintain or build muscle. There is no need to go to the gym every day. Even an extra walk can help burn more fat. 

Conclusion

Nutrition and lifestyle can help you achieve a healthy weight, but this may not work for everyone. Have you tried everything but still cannot lose weight? Do not keep struggling. Perhaps a combination of nutrition,  exercise, and weight loss medication  will help. At Dokteronline, you can complete an online questionnaire. One of our affiliated doctors will review your request and determine whether the chosen treatment is suitable.