Atovaquone Proguanil is a medication that combines two active ingredients, atovaquone, and proguanil, which work together to prevent and treat malaria. Atovaquone interferes with the reproduction of parasites in the body, while proguanil prevents the growth of parasites in the liver. This combination is suitable for individuals traveling to malaria-endemic areas and looking for effective protection against the disease.
About Atovaquone-Proguanil
Dosage and usage
For malaria prevention, the typical adult dosage is one Atovaquone Proguanil tablet once a day, starting one or two days before entering the malaria area, continuing throughout the stay, and for seven days after leaving. Remember to take the tablet with food or a milky drink to improve absorption. It's important not to exceed the recommended dose, as it won't provide additional protection. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In case of vomiting within 1 hour of taking a dose, take another tablet.
What Atovaquone Proguanil contains
Each Atovaquone Proguanil tablet contains 250mg of atovaquone and 100mg of proguanil hydrochloride as the active ingredients. The tablet also includes excipients such as microcrystalline cellulose, poloxamer, povidone K25, sodium starch glycolate, talc, and magnesium stearate.
Side effects
Common side effects of Atovaquone Proguanil may include stomach pain, nausea, vomiting, headache, or diarrhoea. Serious side effects that require immediate medical attention are rare but may include severe skin reactions, liver problems, or blood disorders. If you experience symptoms like persistent vomiting, yellowing of the eyes or skin, or unusual bleeding or bruising, seek medical help promptly.
Precautions
Do not use Atovaquone Proguanil if you are allergic to any of the ingredients, have severe kidney problems, or are pregnant or breastfeeding. This medication is not suitable for children under 11kg in weight. If you have a history of psychiatric disorders, liver disease, or are taking other medications, consult your healthcare provider before using Atovaquone Proguanil to ensure it is safe for you.
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